Liverpool could cope with its first Anfield loss in a year to still overcome Inter Milan and reach the quarterfinals of the Champions League.
Leading 2-0 from the last-16 first leg in Italy, Lautaro Martinez's swerving shot that reduced the deficit in the 61st minute gave the Italian champions hope of a comeback.
But within two minutes, Inter's task was made more difficult when Alexis Sanchez was sent off after his follow-through on Fabinho earned him a second booking.
Liverpool held on to lose 1-0 and advance 2-1 on aggregate. The 2019 Champions League winners are in the quarterfinals for the fourth time in five years despite its first loss in the competition this season.
Liverpool had chances to level. Mohamed Salah volleyed against the post and Luis Diaz's close-range shot was deflected over by Arturo Vidal.
"We struggled in the beginning," Salah said. "We managed to hold the ball up more in the second half. The most important thing is we qualified. Hopefully, we'll be better in the next game."
Inter went out with only the consolation of being the first team to win at Anfield since Fulham 366 days earlier.
"The difficulties we had were pretty close to what I expected," Liverpool manager Jurgen Klopp told broadcaster BT Sport. "Inter are a really good side and set up for these kind of games. They are really fighters and I'm happy we don't play this type of team every week."
Liverpool is still in contention for a quadruple after winning the League Cup last month, then reaching the quarterfinals of the FA Cup and closing Manchester City's lead at the top of the Premier League to six points with a game in hand.
Inter's focus now returns to trying to catch AC Milan in Serie A, with two points to make up and a game in hand.
"We did our best at Anfield," Inter coach Simone Inzaghi said. "And we come out of these two games as a better side, strengthened."
Lewandowski's 11-minute hat trick helps Bayern advance in CL
Whatever hope Salzburg had of overcoming Bayern Munich was extinguished by Robert Lewandowski scoring a hat trick in 11 minutes.
It was game over by the time Lewandowski's third hit the net in the 23rd minute on Tuesday to make it the quickest treble ever seen at the start of a Champions League match.
A second leg that started at 1-1 was tilted 4-1 in Bayern's favour by the striker's scoring masterclass. An 8-2 aggregate win to reach the quarterfinals was completed by further goals from Serge Gnabry, a double from Thomas Muller, and Leroy San. At least Salzburg avoided complete humiliation of not scoring with Maurits Kjaergaard netting for the Austrian team in Bavaria.
Robert Lewandowski's hat-trick inside 23 minutes against Salzburg is the earliest treble ever scored by a player in Champions League history from the start of a match 👏#UCL pic.twitter.com/rX8UFXhOtY
— UEFA Champions League (@ChampionsLeague) March 8, 2022
"That was a statement win," Bayern captain Manuel Neuer said. "I think we showed a different side of ourselves today and didn't concede as many chances on the break. We were also more stable in defence, which obviously gives us hope that things can continue in that vein."
Tuesday's other round of 16 game was far tighter with Liverpool relying on its 2-0 victory at Inter Milan to advance after losing 1-0 at Anfield.
It was three weeks ago when Bayern was reliant on a late equalizer from Kingsley Coman to avoid losing the first leg.
After failing to score—or even hit the target in Salzburg—Lewandowski has now taken his season tally to 42 goals in all competitions.
It took only 12 minutes to score his first against Salzburg, from the penalty spot after being brought down by Maximilian Wober. The defender fouled him again and Lewandowski converted his penalty again in the 21st.
The third came from open play, running onto Muller's pass and then knocking a shot past the advancing goalkeeper Philipp Khn from the edge of the penalty area.
The previous quickest hat trick from the start of a Champions League match came in 24 minutes from Marco Simone for AC Milan against Rosenborg in 1996.
"Today it was an opponent on a different level," Salzburg defender Rasmus Kristensen said. "We had some chances but if you don't make them count, it is difficult. We gave everything but it wasn't enough. It had nothing to do with attitude, focus or the match plan. They simply have been better in all aspects—that's it."
Coman seized the ball off Mohamed Camara to set up Gnabry in the 31st to shoot under Khn.
Muller scored nine minutes into the second half before Kjaergaard struck a superb left-footed consolation for the knockout phase newcomer.
But Muller swept in his 52nd Champions League goal in the 83rd after exchanging passes with Lewandowski and San in the buildup.
The rout was completed with an assist from the striker who started it. Lewandowski back-heeled the ball for San to net the seventh in the 85th.
"Today we had the luck that was completely missing in Salzburg," Muller said.
"We could have gone 1-0 down after five minutes. You're always a little dependent on situations like that, but overall we were better."
