England were six for no loss in their second innings at stumps on the second day of the fourth Test Rose Bowl Cricket Stadium in Southampton on Friday.
Earlier, Cheteshwar Pujara's unbeaten 132 helped India score 273 runs in the first innings and take a 27-run lead.
England, who were all out for 246 in their first innings on Thursday, trailed by 21 runs with 10 wickets remaining.
England 246 and 6 for no loss in 4 overs (Alastair Cook batting 2, Keaton Jennings 4)
India 1st innings: 273 all out in 84.5 overs (Cheteshwar Pujara 132 not out, Virat Kohli 46; Moeen Ali 5/63, Stuart Broad 3/63)